CK-MB/CPK

The CK enzyme consists of isoforms CK-M (muscle) and CK-B (brain), which give rise to the isoenzymes CK-BB, CK-MB, and CK-MM.
The MB or CK2 isoenzyme is also called the cardiac isoenzyme and is one of the components of the CK enzyme,
and its increased level during myocardial cell damage has a higher diagnostic value than CPK alone.
Measuring CK-MB activity, along with measuring CPK, is a highly specific test for diagnosing Heart muscle damage
and, consequently, diagnosing and investigating a heart attack.

LDH

Lactic acid is produced during carbohydrate metabolism mainly by muscle cells and red blood cells and is naturally metabolized in the liver.
The enzyme lactate dehydrogenase (LDH) has five different iso enzymes
and its function is to accelerate the conversion reactions of L-lactate and pyruvate.
LDH is found in the cytoplasm of all body tissues, but its higher concentrations are seen in liver, heart and skeletal muscle tissues
and lower concentrations are seen in pancreas, kidney, stomach and red blood cell tissues.
Pathological increase in LDH activity is seen in many heart, liver, blood, muscle diseases, cancers and heart attacks.
Therefore, the results of this test are valuable in addition to enzyme diagnostic tests such as ALT, ALP, ASAT.